MARG Karaikal Port is connected by major roads to NH-67 at Nagapattinam which is about 10 km from the port.
This link connects MARG Karaikal port to central Tamil Nadu at Trichy.NH-45 which passes through Trichy connects Karaikal to northern hinterland right up till Chennai.
NH-67 starting from Nagapattinam traverses Central Tamil Nadu in a near Straight line connecting the major industrial areas such as Thiruchirapalli, Karur and Coimbatore as well as onward linkages to other industrial areas such as Salem, Erode and Mettur.
Karaikal is also connected all the way to Chennai through NH-45A which passes through Cuddalore. In addition to the national highways, a network of state hichways connects Karaikal to other industrial centre in Tamil Nadu.